divIC [2018-06-04 12:36:06]

cell-division initiation protein (septum formation), component of septosome (with DivIB)

Locus: BSU00620

Isoelectric point: 9.97

Molecular weight: 14.58 kDa

Protein length: 125 aa

Gene length: 375 bp

Function: septum formation

Product: cell-division protein

Essential: yes

Synonyms

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Cell envelope and cell division → Cell division → Other genes
• Lifestyles → Sporulation → Sporulation proteins → Sporulation proteins/ other
• Lifestyles → Coping with stress → Cell envelope stress proteins (controlled by SigM, V, W, X, Y)
• Groups of genes → Essential genes
• Groups of genes → Membrane proteins

Gene

Coordinates: 69,168 → 69,545

Phenotypes of a mutant

• essential PubMed

The protein

Catalyzed reaction/ biological activity

• stabilizes FtsL against RasP cleavage PubMed

Localization

• membrane bound PubMed

Expression and Regulation

Operons

• Genes: yabM-yabN-yabO-yabP-yabQ-divIC-yabR
  Description: PubMed

  Sigma factors

  • SigM: sigma factor, PubMed, in SigM regulon
  • SigE: sigma factor, PubMed, in SigE regulon
  • SigW: sigma factor, PubMed, in SigW regulon
  • SigD: sigma factor, PubMed, in SigD regulon
  • SigX: sigma factor, PubMed, in SigX regulon

  Regulation

  • expressed during sporulation (SigE) PubMed

• Genes: yabP-yabQ-divIC-yabR
  Description: PubMed

  Regulation

  • expressed during sporulation (SigE) PubMed

  Additional information

  • there are about 50,000 molecules of DivIC per cell PubMed

• Genes: divIC-yabR
  Description: PubMed

  Regulation

  • expressed during sporulation (SigE) PubMed and under stress conditions

  Additional information

  • there are about 50,000 molecules of DivIC per cell PubMed

Additional information

• there are about 50,000 molecules of DivIC per cell PubMed

Biological materials

FLAG-tag construct

• GP2006 divIC-3xFLAG ermC (based on pGP1087), available in Jörg Stülke's lab

References

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